The Savannah River Site (SRS) is the location of a government operation that manages US nuclear weapons and related radioactive materials. Ongoing research into safe handling of such materials is an important function of SRS, and this report discusses the Melt-Dilute technology "for the treatment and disposition of aluminum based research and test reactor spent fuel." Each step of the treatment process is described, and it is shown to have applications for a variety of substances. The Melt-Dilute technology can be used to safely transport hazardous materials, and the report favorably evaluates its performance for the Department of Energy.