The Human Genome Center was established in 1991 at the University of Tokyo's Institute of Medical Science. In pursuit of progress in the areas of human disease diagnosis, care, and prevention, the Center conducts genome research in Japan and participates in "international activities in database construction, mapping, and sequencing of the human genome." The Genome Center website contains links to its nine Laboratories which conduct research in the following areas: Genome Structure, Sequence Analysis, Molecular Medicine, and DNA Information Analysis, to name a few. Laboratory pages contain information about research, publications, staff, and services. The Center site also links to a number of databases and software tools including a database of Japanese Single Nucleotide Polymorphisms (JSNP), Microbial Genome Database for Comparative Analysis (MBGD), PSI-BLAST, TFBIND (software for searching transcription factor binding sites), and more.