From the Howard Hughes Medical Institute (HHMI), this website presents the 2004 Holiday Lectures on Science Series. The Series is titled the Science of Fat, and the site includes four webcast lectures by Drs. Ronald M. Evans and Jeffrey M. Friedman of the HHMI. Lecture titles include Deconstructing Obesity; Understanding Fat: Syndrome X and Beyond; Balancing the Fat Equation; and Exploring Obesity: From the Depths of the Brain to the Far Pacific. The original webcast was viewed live by high school students from around the Washington, D.C., area. Site visitors can also link to Holiday Lectures from past years addressing such topics as cancer, neuroscience, gender, biological time, microbes, RNA, and more. The site links to webcasts for a few Informal Talks about a variety of medical issues as well.