2017 marks the tenth anniversary of the Public Library of Science's (PLOS) Neglected Tropical Diseases, which was "the first open access journal devoted to highlighting research and commentary on the forgotten diseases that affect the world's most neglected people." In honor of this anniversary, this open-access journal has published this collection of retrospective articles that highlight research about twenty different tropical diseases and how this research has evolved over the past decade. Readers may want to start by checking out a short history of the journal authored by Peter Hotez and Donald Bundy. From here, readers can find articles about topics including research into parasite genomics, challenges in treating mycetoma, and efforts to eradicate guinea worm. Other articles more broadly address research into tropical diseases, such as Bruce Lee and Sarah Bartsch's "How to determine if a model is right for neglected tropical disease decision making" and Dirk Engels's "Neglected tropical disease: a proxy for economic development and shared prosperity."