From the University of Pittsburgh comes Project Tycho, an ambitious and innovative open data project that "unlocks global health data to a rapidly growing user community of over 3,000 researchers, students, journalists, officials, and others in over 90 countries." Launched in 2013, this project provides access to standardized, pre-compiled datasets for 92 health conditions in the United States and for a range of dengue-related conditions in 99 countries. Users can also compile and download their own datasets from the entire Project Tycho data repository, and they have access to the project's API for further analysis. This data has been used for a variety of scientific research and data visualization projects, and those curious to see what can be done with this information will find nearly 40 examples (as of this write-up) under Featured works. Readers with an interest in data science or public health may be especially likely to find Project Tycho useful. This project is led by Wilbert van Panhuis and Donald Burke as its principal investigators, with Anne Cross as its database manager. Project Tycho is funded by the Bill & Melinda Gates Foundation, the National Institutes of Health, and the Benter Foundation.