Established by Congress after the Apollo spacecraft fire in January 1967, the Aerospace Safety Advisory Panel (ASAP) is an independent group of experts tasked with advising "the NASA Administrator and Congress on all safety-related issues -- design, development, manufacturing, flight preparation, and missions operations -- concerning NASA's human space flight programs." This 130-page report details the Panel's activities for the calendar year 1999. After a thorough introduction, it offers findings and recommendations for the Space Shuttle program, International Space Station (ISS) program, Extravehicular Activity (EVA), Computer Hardware/ Software, and Aero-Space Technology. It also includes information in support of these findings and several appendices.