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Medicine -- Cancer research

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View Resource Briefings in Biotechnology

Profession Carin Zimmerman of the City College of San Francisco has posted materials for a number of her courses online. This one, Briefings in Biotechnology, provides eight lectures covering different topics. Those topics are: environmental technology, quality control, the business of science, a career in industry research, stem cells and cancer, stem cell technology, and drug discovery and...

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http://fog.ccsf.edu/czimmerm/BTEC5BriefingsinBiotechnology.h...
View Resource Mary Beckerle Part 1: Adhesion, Signaling and Cancer

This lecture from the iBioSeminars project is presented by Mary C. Berckerle from the Huntsman Cancer Institute at the University of Utah and covers the cell biology topics of adhesion, signaling and cancer. This first part of this seminar provides a broad overview of the cancer problem for a lay audience. Advances in the understanding of cancer as a genetic disease are discussed. The influence...

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http://www.ibioseminars.org/lectures/cell-bio-a-med/mary-c-b...
View Resource Mary Beckerle Part 2: Discovery and Characterization of a Focal Adhesion Protein Implicated in Tumor Progression

This lecture from the iBioSeminars project is presented by Mary C. Berckerle from the Huntsman Cancer Institute at the University of Utah and covers the identification of the focal adhesion protein, zyxin, by a lab. Recent work revealed that zyxin is down-regulated upon expression of the Ewing sarcoma oncoprotein, EWS-FLI. Loss of zyxin expression results in enhanced cell motility and is also...

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http://www.ibioseminars.org/lectures/cell-bio-a-med/mary-c-b...
View Resource Mary Beckerle Part 3: Focal Adhesions as Stress Sensors

This lecture from the iBioSeminars project is presented by Mary C. Berckerle from the Huntsman Cancer Institute at the University of Utah and covers a new frontier in cell biology; how cells respond to mechanical information. Cells and tissues are exposed to physical forces in vivo and excessive mechanical stress leads to a variety of pathological consequences. Beckerle describes a system for...

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http://www.ibioseminars.org/lectures/cell-bio-a-med/mary-c-b...
View Resource Elizabeth Blackburn Part 2: Telomeres and Telomerase in Human Stem Cells and in Cancer

This lecture from the iBioSeminars project is presented by Elizabeth Blackburn from the University of California, San Francisco Department of Biochemistry and Biophysics. It covers telomerase, a specialized ribonucleprotein reverse transcriptase, important for long-term eukaryotic cell proliferation and genomic stability because it replenishes the DNA at telomeres. Telomerase is highly active in...

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http://www.ibioseminars.org/lectures/cell-bio-a-med/elizabet...
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