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View Resource David Botstein Part 1: Fruits of the Genome Sequences

This lecture from the iBioSeminars project is presented by David Botstein from Princeton University. It presents an overview of the benefits for science and society derived from sequencing the genomes of multiple organisms, including humans. The sequences show that many genes have been conserved during evolution; a finding that allows scientists to study simple organisms such as yeast and relate...

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http://www.ibioseminars.org/lectures/cell-bio-a-med/david-bo...
View Resource J. Michael Bishop Part 3: The Cancer Genome and Therapeutics

This lecture from the iBioSeminars project is presented by J. Michael Bishop of the University of California, San Francisco. It presents experiments to find drugs that exploit vulnerabilities created by cancer genes, utilizing a genetic strategy known as ?synthetic lethality.? This video is the final of three, running a palindromic 31:13 minutes and can be downloaded in QuickTime, MP4, M4V,...

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http://www.ibioseminars.org/lectures/cell-bio-a-med/j-michae...
View Resource J. Michael Bishop Part 2: The Cancer Genome - Challenge and Promise

This lecture from the iBioSeminars project is presented by J. Michael Bishop of the University of California, San Francisco. It presents how the sequencing of cancer genomes will advance the study and management of cancer on various fronts, including the discovery of causes, the improvement of early detection, the prediction of outcome and the development of new therapeutics. Bishop stresses the...

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http://www.ibioseminars.org/lectures/cell-bio-a-med/j-michae...
View Resource J. Michael Bishop Part 1: Forging a Genetic Paradigm for Cancer

This lecture from the iBioSeminars project is presented by J. Michael Bishop of the University of California, San Francisco. It presents a historical review of the experiments that resulted in the realization that cancer has a genetic basis. He explains that mutations can cause normal cellular genes known as proto-oncogenes to become oncogenes, analogous to jammed accelerators causing...

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http://www.ibioseminars.org/lectures/cell-bio-a-med/j-michae...
View Resource David Botstein Part 2: Connecting Growth Control and Stress Response

This lecture from the iBioSeminars project is presented by David Botstein from Princeton University. It presents experiments done in Botstein's lab studying, in yeast, the coordination of growth rate, stress response, metabolism and cell division. Using innovative methods to color code and cluster numerical data from DNA hybridization experiments allows the identification of genes involved in...

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http://ibioseminar.hhmi.org/lectures/cell-bio-a-med/david-bo...
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